An irregular post. pituitary gland can cause which disturbances?

An irregular post. pituitary gland can cause which disturbances?

• A. Hyper: SIADH
• B. Hypo: DI
• C. Both Hyper: SIADH and Hypo: DI
• D. None

Answer: (C)

The posterior pituitary controls the release of antidiuretic hormone (ADH), which tells the kidneys how much water to conserve. If this gland is irregular, ADH output can go up or down. If ADH is released in excess, you get SIADH, where the body holds onto too much water, diluting the blood and lowering sodium, with urine that’s inappropriately concentrated. If ADH release is deficient or ineffective (central diabetes insipidus), the kidneys don’t concentrate urine, leading to large volumes of dilute urine, thirst, and potential dehydration with rising serum osmolality. So a dysfunctional posterior pituitary can produce either hyper-, as in SIADH, or hypo-, as in DI, disturbances.

The posterior pituitary controls the release of antidiuretic hormone (ADH), which tells the kidneys how much water to conserve. If this gland is irregular, ADH output can go up or down. If ADH is released in excess, you get SIADH, where the body holds onto too much water, diluting the blood and lowering sodium, with urine that’s inappropriately concentrated. If ADH release is deficient or ineffective (central diabetes insipidus), the kidneys don’t concentrate urine, leading to large volumes of dilute urine, thirst, and potential dehydration with rising serum osmolality. So a dysfunctional posterior pituitary can produce either hyper-, as in SIADH, or hypo-, as in DI, disturbances.