Which antiemetic is brand-named Zofran?

Which antiemetic is brand-named Zofran?

• A. Promethazine
• B. Diphenhydramine
• C. Loperamide
• D. Ondansetron

Answer: (D)

Zofran is the brand name for ondansetron, an antiemetic that blocks serotonin (5-HT3) receptors to prevent nausea and vomiting, especially after chemotherapy or surgery. By inhibiting these receptors in the gut and the brain’s vomiting center, it stops the signals that would trigger vomiting. The other drugs listed are different types of medications: promethazine and diphenhydramine are antihistamines that can help with nausea in some situations, but they are not Zofran; loperamide is an anti-diarrheal and isn’t used as an antiemetic. So ondansetron matches the brand name Zofran.

Zofran is the brand name for ondansetron, an antiemetic that blocks serotonin (5-HT3) receptors to prevent nausea and vomiting, especially after chemotherapy or surgery. By inhibiting these receptors in the gut and the brain’s vomiting center, it stops the signals that would trigger vomiting. The other drugs listed are different types of medications: promethazine and diphenhydramine are antihistamines that can help with nausea in some situations, but they are not Zofran; loperamide is an anti-diarrheal and isn’t used as an antiemetic. So ondansetron matches the brand name Zofran.